Advertisement

< Back to Article

Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

Figure 3

Comparison of species-specific DHS to independently derived cells.

Human DHS gains show a high level of overlap to DHS regions identified in (a) three independently analyzed human fibroblast cell lines and (b) 5 independently analyzed human LCL samples, compared to human DHS losses. Common DHS are also similarly detected.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1002789.g003