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Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

Figure 3

Comparison of species-specific DHS to independently derived cells.

Human DHS gains show a high level of overlap to DHS regions identified in (a) three independently analyzed human fibroblast cell lines and (b) 5 independently analyzed human LCL samples, compared to human DHS losses. Common DHS are also similarly detected.

Figure 3