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Interpreting Meta-Analyses of Genome-Wide Association Studies

Figure 2

Histograms of m-values of different types of studies.

We assume four types of studies which is the all four combinations of large sample () and small sample (), and effect () and no effect (). We repeatedly simulate a meta-analysis of eight studies, two studies per each type, and calculate the m-values of the studies.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1002555.g002