Temporal Coordination of Gene Networks by Zelda in the Early Drosophila Embryo
Figure 7
Targets of key patterning factors are more likely to be expressed if bound by Zld.
(A) Bar graph showing the number of bound target genes of DV [35] and AP [13], [14] transcription factors (red) that are also bound by Zld (blue) divided into two groups: targets that are expressed (+) or not expressed (−) in blastoderm embryos (from polII ChIP-chip data of [14]). The analysis was restricted to genes within 2 kb of bound regions. (B–C) Heat maps showing the fraction of target genes that two factors have in common, including all target genes (B) or blastoderm-expressed targets (C). The number in each box represents the fraction of genes bound by a factor denoted in the row that are also bound by the factor denoted in the column. For example, 59% of all DTS targets are also bound by Zld (B). This number increases to 76% for those DTS targets that are expressed at 2–4 hrs (C).