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Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila

Figure 2

Lethal stages of various mutants.

The Drosophila life cycle is illustrated, with the lethal stages of different genotypes indicated. The arrows at the bottom left are intended to signify diminishing contribution of maternally-deposited protein. In our crosses, there is no maternal MUS81, but there is half the normal amount of maternal DmBLM, MUS312, and GEN; the developmental stage to which this maternal protein perdures is unknown, and may be different in different tissues.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1002315.g002