An Iterative Genetic and Dynamical Modelling Approach Identifies Novel Features of the Gene Regulatory Network Underlying Melanocyte Development
Figure 12
Revised melanocyte GRN derived from this study.
Components of Factor Y (blue) and Z (red) are indicated. We propose that one or more components of Hdac1-containing repression complex is regulated by Mitfa, and mediates Mitfa-dependent repression of sox10 expression.