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Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease

Figure 5

MAPK interaction networks and degree distribution density curves for the highly-constrained (red) and lowly-constrained (green) genes.

p-values assess the significance of how different the two degree distributions are. The “Mid Variability” genes, falling between the 25th and 75th percentile of CV values, are shown in gray for comparison.

Figure 5

doi: https://doi.org/10.1371/journal.pgen.1002207.g005