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Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease

Figure 1

Plot of -values around rs6812193 and SCARB2.

In the plot, circles represent unannotated SNPs, upside-down triangles represent non-synonymous variants, and boxes with an “x” are SNPs in regions that are highly conserved across 44 placental mammals. Colors depict the squared correlation () of each SNP with the most associated SNP (i.e., rs6812193). Purple designates the SNP with the strongest association, and gray indicates SNPs for which information was missing. Plots were produced using the LocusZoom program [71].

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1002141.g001