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Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins

Figure 3

Phylogenetic tree of NA (subtype N1) illustrating a putatively epistatic interaction between the leading site 344 (red circles) and the trailing site 275 (blue circles).

Other notations are as in Figure 2.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1001301.g003