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The Complex Genetic Architecture of the Metabolome

Figure 8

Genome-wide association hotspots.

Plotted are the average numbers of associated metabolites per gene, estimated at sliding windows of 100 genes, for Expt. A (top) and Expt. B (bottom). Indicated on the axes are previously reported linkage hotspots (red lines; [10]), and two previously reported recent positive selective sweeps (pink S; [60]).

Figure 8

doi: https://doi.org/10.1371/journal.pgen.1001198.g008