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A Survey of Genomic Traces Reveals a Common Sequencing Error, RNA Editing, and DNA Editing

Figure 4

DNA editing in human AluY.

Example of possible DNA editing in human chr21:40977741–40978045. Alignment of trace 1745107496 to the human reference genome lead to large number of G-to-A mismatches which are indications for possible DNA editing in this retrotransposon. All the mismatches are located in high quality sequence positions, reducing the possibility of sequence errors.

Figure 4