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Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci

Figure 6

Chromosome 21q22.13 locus associated with quantitative eye color in the Rotterdam Study (RS123).

The chromosome 21 37.30–37.65 Mb region includes DSCR6, PIGP, TTC3, DSCR9, and DSCR3 genes, SNPs rs1003719, rs2252893, rs2835621, rs2835630, and rs7277820 showed genome-wide significant association with CHS1.

Figure 6