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Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci

Figure 1

The Hue-Saturation (H-S) eye color space in the Rotterdam Study (RS123).

(A) The Hue-Saturation (H-S) eye color space; (B) Example eye photos at their respective position in the H-S space; (C) 3 color categories defined by an ophthalmologist during eye examination and highlighted in the H-S space; (D) 5 categories defined by two researchers from digital full eye size photographs used for digital quantitative extraction of eye colors; (E) 4 quartiles of the 1st principle component CHS1; and (F) 4 quartiles of the 2nd principle component CHS2; all depicted on the H-S color space.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1000934.g001