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Phosphorylation of the Conserved Transcription Factor ATF-7 by PMK-1 p38 MAPK Regulates Innate Immunity in Caenorhabditis elegans

Figure 8

ATF-7 does not contribute to arsenite resistance in C. elegans.

Arsenite stress assay of L4 larval stage wild-type worms; atf-7(qd22 qd130), pmk-1(km25), and sek-1(km4) mutant animals; and atf-7(qd22 qd130); pmk-1(km25) and atf-7(qd22 qd130); sek-1(km4) double mutant animals. Shown is the fraction of worms alive after 18 h. Error bars are standard deviation. The differences in survival between atf-7(qd22 qd130) mutant animals and atf-7(qd22 qd130); pmk-1(km25) double mutant animals, and atf-7(qd22 qd130) mutant animals and atf-7(qd22 qd130); sek-1(km4) double mutant animals are significant (p<0.05 for each comparison).

Figure 8

doi: https://doi.org/10.1371/journal.pgen.1000892.g008