Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response
Figure 6
PHA-4 binding correlates with gene expression levels.
The expression levels of PHA-4 targets show that binding correlates with increased gene expression. Genes bound by PHA-4 specifically in embryos tend to have higher expression (indicated by increasing red intensity) in embryos than in L1s, whereas genes bound specifically in L1s have higher expression in larvae than in embryos. Genes bound at both stages show a mix of expression levels.