U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
Structural variations detected by whole genome sequencing in the U87MG genome are plotted in the Circos program. Orange lines linking two chromosomes represent the 35 interchromosomal translocations. Blue lines around the edge of the circle represent microdeletions and intrachromosomal translocations. The outermost histogram represents sequence coverage and demonstrates how the boundaries of changes in coverage typically coincide with a significant structural variation.