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Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes

Figure 1

Using genome-wide association data to identify natural genetic interactions.

(A) Two interacting interval pairs (green and blue) which represent significantly dense groups of marker-marker interactions are shown. (B) A matrix view of the same genomic regions. The blue and green interval pairs appear as two rectangles. (C) The entire set of marker pairs was bi-clustered to form a set of high-confidence interval pairs (blue rectangles).

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1000782.g001