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Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers

Figure 6

SLIDE's accuracy and efficiency compared to other methods.

We use the WTCCC T2D case/control chromosome 22 data. The vertical axis is the average error in corrected p-values relative to the Bonferroni correction. The horizontal axis is the approximated time for correcting 10 genome-wide p-values for 500 K SNPs assuming 100 K permutations.

Figure 6

doi: https://doi.org/10.1371/journal.pgen.1000456.g006