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Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers

Figure 3

Discrepancy between asymptotic p-value and true p-value in a single SNP experiment.

Given a threshold , the asymptotic p-value is . The true p-value is obtained by listing all possible contingency tables. The number of individuals (N) denotes the number of haplotypes, half control and half case.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1000456.g003