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A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

Figure 6

Kaplan–Meier survival curves for C. elegans treated with RNAi knock-down of genes encoding homologs of six human FRAP1 interacting proteins.

Human homologs corresponding to nematode genes are as follows: MAPKAP2 (C44C8.6); SART3 (B0035.12); ARS2 (E01A2.2); RPS27 (F56E10.4); HYPK (F13G3.10); DKFZP564F0522 (C33H5.10).

Figure 6

doi: https://doi.org/10.1371/journal.pgen.1000414.g006