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The Population Genetics of dN/dS

Figure 3

The relationship between the scaled selection coefficient, γ, and the dN/dS ratio in simulated Wright-Fisher populations.

Black squares show the mean±two standard errors of the observed dN/dS ratio. The predicted dN/dS ratios for divergent lineages are shown in dashed lines (Equation 2); the predicted dN/dS ratios for a single population are shown in solid lines (Equation 5). Left column corresponds to results for two independent populations; right column corresponds to results for a single population. Top panels show results for θ = 0.1; bottom panels show results for θ = 0.01. The simulations for two populations were performed at L = 103 independent sites, and the simulations for a single population were performed at L = 104 independent sites.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1000304.g003