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Identification and Dissection of a Complex DNA Repair Sensitivity Phenotype in Baker's Yeast

Figure 2

Linkage analysis shows that the MMS- and 4-NQO-sensitive phenotypes observed in hybrid progeny are linked to a locus on chromosome 11.

Linkage analysis for A-D was performed using R/qtl. Linkage analysis for sensitivity to MMS (A), 4-NQO (B), bleomycin (C) and caffeine (D) are presented. The red line in each panel indicates a significance cutoff where p = 0.0125 (0.05/the number of traits: 4, Materials and Methods).

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1000123.g002