Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis
Figure 6
Expression of previously published direct MYC targets was permanently repressed or induced upon MYC inactivation in osteosarcomas.
Murine homologs of directed MYC targets identified from 3 publications [33]–[35] were retrieved and their expression in the bone tumors upon MYC inactivation and reactivation was examined. Genes scored statistically significant (p<0.01) in the StepMiner analysis were labeled.