Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

• Mitesh J. Borad ,

  Contributed equally to this work with: Mitesh J. Borad, Mia D. Champion, Jan B. Egan

  * E-mail: borad.mitesh@mayo.edu (MJB); jcarpten@tgen.org (JDC)

  Affiliations Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America, Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Mia D. Champion ,

  Contributed equally to this work with: Mitesh J. Borad, Mia D. Champion, Jan B. Egan

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Jan B. Egan ,

  Contributed equally to this work with: Mitesh J. Borad, Mia D. Champion, Jan B. Egan

  Affiliation Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Winnie S. Liang,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Rafael Fonseca,

  Affiliations Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America, Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Alan H. Bryce,

  Affiliations Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America, Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Ann E. McCullough,

  Affiliation Department of Pathology, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Michael T. Barrett,

  Affiliations Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Katherine Hunt,

  Affiliation Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Maitray D. Patel,

  Affiliation Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Scott W. Young,

  Affiliation Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Joseph M. Collins,

  Affiliation Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Alvin C. Silva,

  Affiliation Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Rachel M. Condjella,

  Affiliation Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America

  ⨯
• Matthew Block,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America

  ⨯
• Robert R. McWilliams,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America

  ⨯
• Konstantinos N. Lazaridis,

  Affiliation Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Eric W. Klee,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Keith C. Bible,

  Affiliation Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America

  ⨯
• Pamela Harris,

  Affiliation Investigational Drug Branch, National Cancer Institute, Rockville, Maryland, United States of America

  ⨯
• Gavin R. Oliver,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Jaysheel D. Bhavsar,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Asha A. Nair,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Sumit Middha,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Yan Asmann,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Jean-Pierre Kocher,

  Affiliations Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America

  ⨯
• Kimberly Schahl,

  Affiliation Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Benjamin R. Kipp,

  Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Emily G. Barr Fritcher,

  Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Angela Baker,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Jessica Aldrich,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Ahmet Kurdoglu,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Tyler Izatt,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Alexis Christoforides,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Irene Cherni,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Sara Nasser,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Rebecca Reiman,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Lori Phillips,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Jackie McDonald,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Jonathan Adkins,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Stephen D. Mastrian,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Pamela Placek,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Aprill T. Watanabe,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Janine LoBello,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Haiyong Han,

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• Daniel Von Hoff,

  Affiliations Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• David W. Craig ,

  ¶DWC and JDC also contributed equally.

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• A. Keith Stewart,

  Affiliations Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America, Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
•  [ ... ],
• John D. Carpten

  * E-mail: borad.mitesh@mayo.edu (MJB); jcarpten@tgen.org (JDC)

  ¶DWC and JDC also contributed equally.

  Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America

  ⨯
• [ view all ]
• [ view less ]