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Open Access
Peer-reviewed
Research Article
Mislocalization of XPF-ERCC1 Nuclease Contributes to Reduced DNA Repair in XP-F Patients
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Anwaar Ahmad ,
Contributed equally to this work with: Anwaar Ahmad, Jacqueline H. Enzlin, Nikhil R. Bhagwat
Affiliations Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
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Jacqueline H. Enzlin ,
Contributed equally to this work with: Anwaar Ahmad, Jacqueline H. Enzlin, Nikhil R. Bhagwat
Current address: Cancer Research UK, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
Affiliation Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland
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Nikhil R. Bhagwat ,
Contributed equally to this work with: Anwaar Ahmad, Jacqueline H. Enzlin, Nikhil R. Bhagwat
Affiliations Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America
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Nils Wijgers,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Anja Raams,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Esther Appledoorn,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Arjan F. Theil,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Jan H. J. Hoeijmakers,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Wim Vermeulen,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Nicolaas G. J. Jaspers,
Affiliation Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
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Orlando D. Schärer ,
* E-mail: niedernhoferl@upmc.edu (LJN); orlando@pharm.stonybrook.edu (ODS)
Affiliation Departments of Pharmacological Sciences and Chemistry, Stony Brook University, Stony Brook, New York, United States of America
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Laura J. Niedernhofer
* E-mail: niedernhoferl@upmc.edu (LJN); orlando@pharm.stonybrook.edu (ODS)
Affiliations Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands, Departments of Pharmacological Sciences and Chemistry, Stony Brook University, Stony Brook, New York, United States of America
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Mislocalization of XPF-ERCC1 Nuclease Contributes to Reduced DNA Repair in XP-F Patients
- Anwaar Ahmad,
- Jacqueline H. Enzlin,
- Nikhil R. Bhagwat,
- Nils Wijgers,
- Anja Raams,
- Esther Appledoorn,
- Arjan F. Theil,
- Jan H. J. Hoeijmakers,
- Wim Vermeulen,
- Nicolaas G. J. Jaspers
- Published: March 5, 2010
- https://doi.org/10.1371/journal.pgen.1000871