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Open Access
Peer-reviewed
Research Article
A Systematic Approach to Mapping Recessive Disease Genes in Individuals from Outbred Populations
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Friedhelm Hildebrandt ,
* E-mail: fhilde@umich.edu
Affiliations Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America, Howard Hughes Medical Institute, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Saskia F. Heeringa,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Franz Rüschendorf,
Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany
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Massimo Attanasio,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Gudrun Nürnberg,
Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Institute for Genetics, University of Cologne, Cologne, Germany
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Christian Becker,
Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Institute for Genetics, University of Cologne, Cologne, Germany
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Dominik Seelow,
Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Institute for Genetics, University of Cologne, Cologne, Germany, Department of Neuropaediatrics, Charite, Berlin, Germany
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Norbert Huebner,
Affiliation Department of Pediatrics, Charite, Berlin, Germany
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Gil Chernin,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Christopher N. Vlangos,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Weibin Zhou,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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John F. O'Toole,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Bethan E. Hoskins,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Matthias T. F. Wolf,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Bernward G. Hinkes,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Hassan Chaib,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Shazia Ashraf,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Dominik S. Schoeb,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Bugsu Ovunc,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Susan J. Allen,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Virginia Vega-Warner,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Eric Wise,
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Heather M. Harville,
Affiliations Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Robert H. Lyons,
Affiliation Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Joseph Washburn,
Affiliation University of Michigan Cancer Center, Ann Arbor, Michigan, United States of America
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James MacDonald,
Affiliations Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America, University of Michigan Cancer Center, Ann Arbor, Michigan, United States of America
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Peter Nürnberg,
Affiliations Cologne Center for Genomics, University of Cologne, Cologne, Germany, Institute for Genetics, University of Cologne, Cologne, Germany
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Edgar A. Otto
Affiliation Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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A Systematic Approach to Mapping Recessive Disease Genes in Individuals from Outbred Populations
- Friedhelm Hildebrandt,
- Saskia F. Heeringa,
- Franz Rüschendorf,
- Massimo Attanasio,
- Gudrun Nürnberg,
- Christian Becker,
- Dominik Seelow,
- Norbert Huebner,
- Gil Chernin,
- Christopher N. Vlangos
- Published: January 23, 2009
- https://doi.org/10.1371/journal.pgen.1000353