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Open Access
Peer-reviewed
Research Article
Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol
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Sumeet A. Khetarpal ,
Contributed equally to this work with: Sumeet A. Khetarpal, Andrew C. Edmondson
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Andrew C. Edmondson ,
Contributed equally to this work with: Sumeet A. Khetarpal, Andrew C. Edmondson
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Avanthi Raghavan,
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Hemanth Neeli,
Affiliation Section of Hospital Medicine, Temple University Hospital, Philadelphia, Pennsylvania, United States of America
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Weijun Jin,
Affiliation Department of Cell Biology, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America
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Karen O. Badellino,
Affiliation University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, United States of America
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Serkalem Demissie,
Affiliations Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, United States of America
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Alisa K. Manning,
Affiliation Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
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Stephanie L. DerOhannessian,
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Megan L. Wolfe,
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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L. Adrienne Cupples,
Affiliations Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, United States of America
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Mingyao Li,
Affiliation Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Sekar Kathiresan,
Affiliations Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
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Daniel J. Rader
* E-mail: rader@mail.med.upenn.edu
Affiliation Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity, and Metabolism, and Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol
- Sumeet A. Khetarpal,
- Andrew C. Edmondson,
- Avanthi Raghavan,
- Hemanth Neeli,
- Weijun Jin,
- Karen O. Badellino,
- Serkalem Demissie,
- Alisa K. Manning,
- Stephanie L. DerOhannessian,
- Megan L. Wolfe
- Published: December 8, 2011
- https://doi.org/10.1371/journal.pgen.1002393