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Open Access
Peer-reviewed
Research Article
Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
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Undine Kruegel ,
Contributed equally to this work with: Undine Kruegel, Brett Robison
Affiliation Department of Biochemistry, Albert Einstein College of Medicine, New York, New York, United States of America
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Brett Robison ,
Contributed equally to this work with: Undine Kruegel, Brett Robison
Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, Buck Institute, Novato, California, United States of America
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Thomas Dange,
Current address: Kavli Institute of NanoScience, Department of BioNanoScience, Delft University of Technology, Delft, The Netherlands
Affiliation Department of Biochemistry, Albert Einstein College of Medicine, New York, New York, United States of America
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Günther Kahlert,
Affiliation Max Delbrueck Center for Molecular Medicine, Berlin, Germany
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Joe R. Delaney,
Affiliations Department of Pathology, University of Washington, Seattle, Washington, United States of America, Department of Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America
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Soumya Kotireddy,
Affiliation Department of Biochemistry, University of Washington, Seattle, Washington, United States of America
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Mitsuhiro Tsuchiya,
Affiliation Buck Institute, Novato, California, United States of America
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Scott Tsuchiyama,
Affiliation Buck Institute, Novato, California, United States of America
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Christopher J. Murakami,
Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Jennifer Schleit,
Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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George Sutphin,
Affiliations Department of Pathology, University of Washington, Seattle, Washington, United States of America, Department of Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America
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Daniel Carr,
Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Krisztina Tar,
Affiliation Department of Biochemistry, Albert Einstein College of Medicine, New York, New York, United States of America
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Gunnar Dittmar,
Affiliation Max Delbrueck Center for Molecular Medicine, Berlin, Germany
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Matt Kaeberlein ,
* E-mail: marion.schmidt@einstein.yu.edu (MS); bkennedy@buckinstitute.org (BKK); kaeber@u.washington.edu (MK)
Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Brian K. Kennedy ,
* E-mail: marion.schmidt@einstein.yu.edu (MS); bkennedy@buckinstitute.org (BKK); kaeber@u.washington.edu (MK)
Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, Buck Institute, Novato, California, United States of America
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Marion Schmidt
* E-mail: marion.schmidt@einstein.yu.edu (MS); bkennedy@buckinstitute.org (BKK); kaeber@u.washington.edu (MK)
Affiliation Department of Biochemistry, Albert Einstein College of Medicine, New York, New York, United States of America
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Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
- Undine Kruegel,
- Brett Robison,
- Thomas Dange,
- Günther Kahlert,
- Joe R. Delaney,
- Soumya Kotireddy,
- Mitsuhiro Tsuchiya,
- Scott Tsuchiyama,
- Christopher J. Murakami,
- Jennifer Schleit
- Published: September 8, 2011
- https://doi.org/10.1371/journal.pgen.1002253