From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

Zhi Wei; Kai Wang; Hui-Qi Qu; Haitao Zhang; Jonathan Bradfield; Cecilia Kim; Edward Frackleton; Cuiping Hou; Joseph T. Glessner; Rosetta Chiavacci; Charles Stanley; Dimitri Monos; Struan F. A. Grant; Constantin Polychronakos; Hakon Hakonarson

doi:10.1371/journal.pgen.1000678

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Peer-reviewed

Research Article

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

Zhi Wei ,

Contributed equally to this work with: Zhi Wei, Kai Wang

Affiliation Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, United States of America
⨯
Kai Wang ,

Contributed equally to this work with: Zhi Wei, Kai Wang

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Hui-Qi Qu,

Affiliation Departments of Pediatrics and Human Genetics, McGill University, Montreal, Québec, Canada
⨯
Haitao Zhang,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Jonathan Bradfield,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Cecilia Kim,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Edward Frackleton,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Cuiping Hou,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Joseph T. Glessner,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Rosetta Chiavacci,

Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Charles Stanley,

Affiliation Division of Endocrinology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Dimitri Monos,

Affiliation Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Struan F. A. Grant,

Affiliations Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Constantin Polychronakos,

Affiliation Departments of Pediatrics and Human Genetics, McGill University, Montreal, Québec, Canada
⨯
Hakon Hakonarson

* E-mail: hakonarson@chop.edu

Affiliations Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

Zhi Wei,
Kai Wang,
Hui-Qi Qu,
Haitao Zhang,
Jonathan Bradfield,
Cecilia Kim,
Edward Frackleton,
Cuiping Hou,
Joseph T. Glessner,
Rosetta Chiavacci

Published: October 9, 2009
https://doi.org/10.1371/journal.pgen.1000678

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27 Nov 2009
20:32 GMT
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Stability metrics Posted by biostats on 27 Nov 2009 at 20:32 GMT

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