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Posted by PLOS_Genetics on 20 Mar 2009 at 10:04 GMT

We have demonstrated here that complex animal regulatory sequences can tolerate nearly complete rearrangement of their transcription factor binding sites without appreciably altering their transcriptional output.
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000106#article1.body1.sec3.p1

- A Closer Look at the eve Stripe 2 Enhancers of Drosophila and Themira (http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000276)

- A Careful Look at Binding Site Reorganization in the even-skipped Enhancers of Drosophila and Sepsids (http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000268)

No competing interests declared.