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Open Access
Peer-reviewed
Research Article
Genomic Hypomethylation in the Human Germline Associates with Selective Structural Mutability in the Human Genome
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Jian Li,
Affiliations Bioinformatics Research Laboratory, Epigenome Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
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R. Alan Harris,
Affiliations Bioinformatics Research Laboratory, Epigenome Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Sau Wai Cheung,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Cristian Coarfa,
Affiliations Bioinformatics Research Laboratory, Epigenome Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Mira Jeong,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Margaret A. Goodell,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Lisa D. White,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Ankita Patel,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Sung-Hae Kang,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Chad Shaw,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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A. Craig Chinault,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Tomasz Gambin,
Affiliation Institute of Computer Science, Warsaw University of Technology, Warsaw, Poland
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Anna Gambin,
Affiliation Institute of Informatics, Warsaw University, Warsaw, Poland
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James R. Lupski,
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Texas Children's Hospital, Houston, Texas, United States of America
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Aleksandar Milosavljevic
* E-mail: amilosav@bcm.edu
Affiliations Bioinformatics Research Laboratory, Epigenome Center, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
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Genomic Hypomethylation in the Human Germline Associates with Selective Structural Mutability in the Human Genome
- Jian Li,
- R. Alan Harris,
- Sau Wai Cheung,
- Cristian Coarfa,
- Mira Jeong,
- Margaret A. Goodell,
- Lisa D. White,
- Ankita Patel,
- Sung-Hae Kang,
- Chad Shaw
- Published: May 17, 2012
- https://doi.org/10.1371/journal.pgen.1002692