A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

Grace X. Y. Zheng; Arvind Ravi; J. Mauro Calabrese; Lea A. Medeiros; Oktay Kirak; Lucas M. Dennis; Rudolf Jaenisch; Christopher B. Burge; Phillip A. Sharp

doi:10.1371/journal.pgen.1002054

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Research Article

A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

Grace X. Y. Zheng ,

Contributed equally to this work with: Grace X. Y. Zheng, Arvind Ravi

Current address: Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford School of Medicine, Stanford, California, United States of America

Affiliations MIT Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts, United States of America, Computational and Systems Biology Graduate Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Arvind Ravi ,

Contributed equally to this work with: Grace X. Y. Zheng, Arvind Ravi

Affiliations MIT Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Harvard-MIT Health Sciences and Technology Program, Cambridge, Massachusetts, United States of America
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J. Mauro Calabrese,

Current address: Department of Genetics and the Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina, United States of America

Affiliations MIT Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Lea A. Medeiros,

Affiliations Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
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Oktay Kirak,

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
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Lucas M. Dennis,

Current address: NanoString Technologies, Seattle, Washington, United States of America

Affiliations Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
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Rudolf Jaenisch,

Affiliations Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
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Christopher B. Burge,

Affiliations Computational and Systems Biology Graduate Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Phillip A. Sharp

* E-mail: sharppa@mit.edu

Affiliations MIT Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

Grace X. Y. Zheng,
Arvind Ravi,
J. Mauro Calabrese,
Lea A. Medeiros,
Oktay Kirak,
Lucas M. Dennis,
Rudolf Jaenisch,
Christopher B. Burge,
Phillip A. Sharp

Published: May 5, 2011
https://doi.org/10.1371/journal.pgen.1002054

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Posted by PLOS_Genetics on 15 Jul 2011 at 14:28 GMT

Microarray analysis
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002054#article1.body1.sec4.sec9.p1

Microarray data are available in the GEO repository under the accession number: GSE30012.

No competing interests declared.

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A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

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Accession Numbers

Posted by PLOS_Genetics on 15 Jul 2011 at 14:28 GMT