The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

Andreas Rechtsteiner; Sevinc Ercan; Teruaki Takasaki; Taryn M. Phippen; Thea A. Egelhofer; Wenchao Wang; Hiroshi Kimura; Jason D. Lieb; Susan Strome

doi:10.1371/journal.pgen.1001091

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Research Article

The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

Andreas Rechtsteiner ,

Contributed equally to this work with: Andreas Rechtsteiner, Sevinc Ercan, Teruaki Takasaki

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Sevinc Ercan ,

Contributed equally to this work with: Andreas Rechtsteiner, Sevinc Ercan, Teruaki Takasaki

Affiliation Department of Biology, Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Teruaki Takasaki ,

Contributed equally to this work with: Andreas Rechtsteiner, Sevinc Ercan, Teruaki Takasaki

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Taryn M. Phippen,

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Thea A. Egelhofer,

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Wenchao Wang,

Current address: Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Hiroshi Kimura,

Affiliation Graduate School for Frontier Biosciences, Osaka University, Suita, Osaka, Japan
⨯
Jason D. Lieb ,

* E-mail: strome@biology.ucsc.edu (SS); jlieb@bio.unc.edu (JDL)

Affiliation Department of Biology, Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Susan Strome

* E-mail: strome@biology.ucsc.edu (SS); jlieb@bio.unc.edu (JDL)

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯

The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

Andreas Rechtsteiner,
Sevinc Ercan,
Teruaki Takasaki,
Taryn M. Phippen,
Thea A. Egelhofer,
Wenchao Wang,
Hiroshi Kimura,
Jason D. Lieb,
Susan Strome

Published: September 2, 2010
https://doi.org/10.1371/journal.pgen.1001091

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Posted by strome on 05 Sep 2010 at 15:29 GMT

Furuhashi et al., unpublished
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001091#article1.body1.sec3.p7

Furuhashi, H., T. Takasaki, A. Rechtsteiner, T. Li, H. Kimura, P. Checchi, S. Strome, and W.G. Kelly. 2010. Trans-generational epigenetic regulation of C. elegans primordial germ cells. Epigenetics and Chromatin 3: 15.

No competing interests declared.

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Gene expression
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Embryos
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Methylation
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X chromosomes
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Chromatin
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DNA transcription
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Histones
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The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

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Posted by strome on 05 Sep 2010 at 15:29 GMT