About the Authors

Fan Yang

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada

Song Sun

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

Guihong Tan

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Michael Costanzo

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

David E. Hill

Affiliations Center for Cancer Systems Biology (CCSB), Dana- Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

ORCID http://orcid.org/0000-0001-5192-0921

Marc Vidal

Affiliations Center for Cancer Systems Biology (CCSB), Dana- Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Brenda J. Andrews

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

Charles Boone

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Canadian Institute for Advanced Research, Toronto, Ontario, Canada

Frederick P. Roth

fritz.roth@utoronto.ca

Affiliations Donnelly Centre, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada, Center for Cancer Systems Biology (CCSB), Dana- Farber Cancer Institute, Boston, Massachusetts, United States of America, Canadian Institute for Advanced Research, Toronto, Ontario, Canada

ORCID http://orcid.org/0000-0002-6628-649X

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: FY SS FPR. Formal analysis: FY. Investigation: FY GT MC BJA CB DEH MV. Writing – original draft: FY. Writing – review & editing: FPR FY SS GT MC DEH MV BJA CB.