About the Authors

Matthias C. Truttmann

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Victor E. Cruz

Affiliation Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, United States of America

Xuanzong Guo

Affiliation Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, United States of America

Christoph Engert

Affiliation Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, United States of America

Thomas U. Schwartz

Affiliation Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, United States of America

Hidde L. Ploegh

ploegh@wi.mit.edu

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MCT VEC CE TUS HLP. Performed the experiments: MCT VEC XG CE. Analyzed the data: MCT VEC TUS HLP. Contributed reagents/materials/analysis tools: MCT VEC XG CE. Wrote the paper: MCT VEC TUS HLP. Solved crystal structure of FIC-1: VEC XG TUS.