About the Authors

Maja L. Arendt

maja-louise.arendt@imbim.uu.se (MLA); kersli@broadinstitute.org (KLT)

Affiliations Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Malin Melin

Affiliation Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

Noriko Tonomura

Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts, United States of America

Michele Koltookian

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Celine Courtay-Cahen

Affiliation Animal Health Trust, Newmarket, United Kingdom

Netty Flindall

Affiliation Animal Health Trust, Newmarket, United Kingdom

Joyce Bass

Affiliation Animal Health Trust, Newmarket, United Kingdom

Kim Boerkamp

Affiliation Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands

Katherine Megquir

Affiliations Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts, United States of America

Lisa Youell

Affiliation Animal Health Trust, Newmarket, United Kingdom

Sue Murphy

Affiliation Animal Health Trust, Newmarket, United Kingdom

Colleen McCarthy

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Cheryl London

Affiliation Department of Veterinary Clinical Sciences Ohio State University, Columbus, Ohio, United States of America

Gerard R. Rutteman

Affiliations Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands, Veterinary Specialist Center De Wagenrenk, Wageningen, The Netherlands

Mike Starkey

‡ These authors are joint senior authors on this work.

Affiliation Animal Health Trust, Newmarket, United Kingdom

Kerstin Lindblad-Toh

maja-louise.arendt@imbim.uu.se (MLA); kersli@broadinstitute.org (KLT)

‡ These authors are joint senior authors on this work.

Affiliations Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Competing Interests

A patent application has been filed related to this work patent application number B1195.70019US00.

Author Contributions

Conceived and designed the experiments: MA MM NT MS KLT. Performed the experiments: MA AF JB. Analyzed the data: MA MM KLT. Contributed reagents/materials/analysis tools: NT MK LY KB KM SM CM CL GRR MS MP NT MM MS CCC KB. Wrote the paper: MA MM KLT. Oversaw the study: KLT MS. Performed the RNA work and sequence capture: MA. Performed the histochemical staining: FA BJ. Collected and characterized samples for the study: NT MK LY KB KM SM CM CL GRR MS. Selected and prepared samples for genotyping and managed data generation: MK NT MM MS CCC KB GRR. Contributed in editing the paper: MA MM NT MK CCC AF JB KB KM LY SM CM CL GRR MS KLT.