About the Authors

Lydia M. Castelli

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

David Talavera

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Christopher J. Kershaw

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Sarah S. Mohammad-Qureshi

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Joseph L. Costello

Current address: Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

William Rowe

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Paul F. G. Sims

Affiliations The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom, Manchester Institute of Biotechnology (MIB), The University of Manchester, Manchester, United Kingdom

Christopher M. Grant

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Simon J. Hubbard

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Mark P. Ashe

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Graham D. Pavitt

graham.pavitt@manchester.ac.uk

Affiliation The Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GDP MPA CMG SJH PFGS LMC CJK SSMQ. Performed the experiments: LMC DT CJK SSMQ JLC. Analyzed the data: GDP LMC DT SSMQ CJK JLC SJH WR MPA CMG PFGS. Wrote the paper: GDP LMC DT SSMQ CJK. Contributed modifications to the text: CJK CMG PFGS DT SJH MPA.