About the Authors

Xiaomu Wei

Contributed equally to this work with: Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang

Affiliations Department of Medicine, Weill Cornell College of Medicine, New York, New York, United States of America, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America

Jishnu Das

Contributed equally to this work with: Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Robert Fragoza

Contributed equally to this work with: Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Jin Liang

Contributed equally to this work with: Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang

Affiliation Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America

Francisco M. Bastos de Oliveira

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Hao Ran Lee

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Xiujuan Wang

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Matthew Mort

Affiliation Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff, United Kingdom

Peter D. Stenson

Affiliation Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff, United Kingdom

David N. Cooper

Affiliation Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff, United Kingdom

Steven M. Lipkin

Affiliation Department of Medicine, Weill Cornell College of Medicine, New York, New York, United States of America

Marcus B. Smolka

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

Haiyuan Yu

haiyuan.yu@cornell.edu

Affiliations Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XWe HY MBS. Performed the experiments: XWe RF JL FMBdO. Analyzed the data: JD. Contributed reagents/materials/analysis tools: HRL XWa MM PDS DNC SML. Wrote the paper: HY JD. Conceived the study and oversaw all aspects of the project: HY.