About the Authors

Claire Chewapreecha

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Pekka Marttinen

Affiliations Center for Communicable Disease Dynamics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Helsinki Institute for Information Technology HIIT, Department of Information and Computer Science, Aalto University, Espoo, Finland

Nicholas J. Croucher

Affiliation Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

Susannah J. Salter

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Simon R. Harris

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Alison E. Mather

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

William P. Hanage

Affiliation Center for Communicable Disease Dynamics, Harvard School of Public Health, Boston, Massachusetts, United States of America

David Goldblatt

Affiliation Immunobiology Unit, Institute of Child Health, University College London, London, United Kingdom

Francois H. Nosten

Affiliations Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Maesot, Thailand, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Claudia Turner

Affiliations Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Maesot, Thailand, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia

Paul Turner

Contributed equally to this work with: Paul Turner, Stephen D. Bentley, Julian Parkhill

Affiliations Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Maesot, Thailand, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia

Stephen D. Bentley

Contributed equally to this work with: Paul Turner, Stephen D. Bentley, Julian Parkhill

sdb@sanger.ac.uk (SDB); parkhill@sanger.ac.uk (JP)

Affiliations The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Julian Parkhill

Contributed equally to this work with: Paul Turner, Stephen D. Bentley, Julian Parkhill

sdb@sanger.ac.uk (SDB); parkhill@sanger.ac.uk (JP)

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JP SDB PT CT FHN DG CC FN. Performed the experiments: CC SJS. Analyzed the data: CC PM NJC SRH AEM WPH JP. Contributed reagents/materials/analysis tools: PM AEM SRH PT CT WPH. Wrote the paper: CC JP. Prepared sequence data: CC NJC. Read and approved the manuscript: CC PM NJC SJS SRH AEM WPH DG FHN CT PT SDB JP.