About the Authors

Julien Bryois

Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland

Alfonso Buil

Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland

David M. Evans

Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia

John P. Kemp

Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Stephen B. Montgomery

Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Department of Pathology and Genetics, Stanford University, Stanford, California, United States of America

Donald F. Conrad

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Karen M. Ho

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Susan Ring

Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Matthew Hurles

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Panos Deloukas

Affiliations Wellcome Trust Sanger Institute, Hinxton, United Kingdom, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kindom, Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia

George Davey Smith

Affiliations MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Emmanouil T. Dermitzakis

emmanouil.dermitzakis@unige.ch

Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland, Swiss Institute of Bioinformatics (SIB), Geneva, Switzerland, Center of Excellence for Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ETD GDS PD MH SR. Performed the experiments: JPK KMH DFC. Analyzed the data: JB AB DME JPK SBM DFC. Contributed reagents/materials/analysis tools: SR MH PD GDS ETD. Wrote the paper: JB DME ETD.