About the Authors

Johann de Jong

Contributed equally to this work with: Johann de Jong, Waseem Akhtar

Affiliations Computational Cancer Biology Group, Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Netherlands Consortium for Systems Biology, Amsterdam, The Netherlands

Waseem Akhtar

Contributed equally to this work with: Johann de Jong, Waseem Akhtar

Affiliations Netherlands Consortium for Systems Biology, Amsterdam, The Netherlands, Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Jitendra Badhai

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Alistair G. Rust

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton-Cambridge, United Kingdom

Roland Rad

Affiliation Department of Medicine II; Klinikum Rechts der Isar; Technische Universität München, German Cancer Research Center (DKFZ), Heidelberg, & German Cancer Consortium (DKTK), Heidelberg, Germany

John Hilkens

Affiliation Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Anton Berns

Affiliations Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Skoltech Center for Stem Cell Research, Skolkovo Institute for Science and Technology, Skolkovo, Odintsovsky, Moscow, Russia

Maarten van Lohuizen

Affiliations Netherlands Consortium for Systems Biology, Amsterdam, The Netherlands, Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Lodewyk F. A. Wessels

l.wessels@nki.nl (LFAW); j.deridder@tudelft.nl (JdR)

Affiliations Computational Cancer Biology Group, Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands, Netherlands Consortium for Systems Biology, Amsterdam, The Netherlands, Delft Bioinformatics Lab, Faculty of EEMCS, TU Delft, Delft, The Netherlands

Jeroen de Ridder

l.wessels@nki.nl (LFAW); j.deridder@tudelft.nl (JdR)

Affiliation Delft Bioinformatics Lab, Faculty of EEMCS, TU Delft, Delft, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LFAW MvL. Performed the experiments: WA. Analyzed the data: JdJ WA. Contributed reagents/materials/analysis tools: JB. Wrote the paper: JdJ WA. Processed the SB tumor screen: AGR. Generated and processed the PB tumor screen: RR. Provided the strategy for generating the MMTV integration dataset: JH. Co-wrote the manuscript: JdR LFAW. Supervised the computational analyses: JdR LFAW. Supervised the project: AB MvL LFAW JdR.