About the Authors
- Leonardo Bottolo
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Contributed equally to this work with: Leonardo Bottolo, Marc Chadeau-Hyam
* E-mail: l.bottolo@imperial.ac.uk (LB); sylvia@mrc-bsu.cam.ac.uk (SR)
Affiliation Department of Mathematics, Imperial College London, London, United Kingdom
- Marc Chadeau-Hyam
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Contributed equally to this work with: Leonardo Bottolo, Marc Chadeau-Hyam
Affiliation Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
- David I. Hastie
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Affiliation Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
- Tanja Zeller
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Affiliation University Heart Center Hamburg, Department of General and Interventional Cardiology, Hamburg, Germany
- Benoit Liquet
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Affiliations INSERM U897, University Victor Segalen, Bordeaux, France, MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom
- Paul Newcombe
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Affiliation MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom
- Loic Yengo
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Affiliations European Genomic Institute for Diabetes, Lille, France, CNRS UMR 8199 - Institut Pasteur de Lille, Lille, France
- Philipp S. Wild
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Affiliation Clinical Epidemiology, Center for Thrombosis and Haemostasis, University Medical Center Mainz, Mainz, Germany
- Arne Schillert
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Affiliation Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany
- Andreas Ziegler
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Affiliation Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany
- Sune F. Nielsen
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Affiliations Department of Clinical Biochemistry, Herlev Hospital, Copenhagen, Denmark, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark
- Adam S. Butterworth
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Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
- Weang Kee Ho
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Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
- Raphaële Castagné
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Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France
- Thomas Munzel
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Affiliation Department of Medicine II, University Medical Center Mainz, Mainz, Germany
- David Tregouet
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Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
- Mario Falchi
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Affiliation Department of Genomics of Common Disease, School Of Public Health, Hammersmith Hospital, Imperial College London, London, United Kingdom
- François Cambien
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Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France
- Børge G. Nordestgaard
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Affiliations Department of Clinical Biochemistry, Herlev Hospital, Copenhagen, Denmark, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark
- Fredéric Fumeron
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Affiliations INSERM U695, Paris, France, Université Paris Diderot-Paris 7, UFR de Médecine Site Bichat, Paris, France
- Anne Tybjærg-Hansen
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Affiliation Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark
- Philippe Froguel
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Affiliations European Genomic Institute for Diabetes, Lille, France, CNRS UMR 8199 - Institut Pasteur de Lille, Lille, France, Department of Genomics of Common Disease, School Of Public Health, Hammersmith Hospital, Imperial College London, London, United Kingdom, Université de Lille 2, Lille, France
- John Danesh
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Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
- Enrico Petretto
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Affiliation Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom
- Stefan Blankenberg
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Affiliation University Heart Center Hamburg, Department of General and Interventional Cardiology, Hamburg, Germany
- Laurence Tiret
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Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6), Paris, France
- Sylvia Richardson
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* E-mail: l.bottolo@imperial.ac.uk (LB); sylvia@mrc-bsu.cam.ac.uk (SR)
Affiliation MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: LB SR LT FC DT EP. Analyzed the data: LB MCH DIH BL PN LY RC MF. Contributed reagents/materials/analysis tools: MCH DIH LB. Wrote the paper: LB SR LT EP. Gutenberg Health Study (GHS) data generation: SB TZ PSW AS AZ TM. Copenhagen City Heart Study (CCHS) data generation: JD ASB WKH SFN BGN ATH. Data from an Epidemiological Study on the Insulin Resistance syndrome (DESIR) data generation: PF FF.