About the Authors
- Niels Grarup
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Contributed equally to this work with: Niels Grarup, Patrick Sulem, Camilla H. Sandholt
Affiliation The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Patrick Sulem
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Contributed equally to this work with: Niels Grarup, Patrick Sulem, Camilla H. Sandholt
Affiliation deCODE Genetics, Reykjavik, Iceland
- Camilla H. Sandholt
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Contributed equally to this work with: Niels Grarup, Patrick Sulem, Camilla H. Sandholt
Affiliation The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Gudmar Thorleifsson
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Tarunveer S. Ahluwalia
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Affiliation The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Valgerdur Steinthorsdottir
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Helgi Bjarnason
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Daniel F. Gudbjartsson
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Olafur T. Magnusson
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Thomas Sparsø
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Affiliation The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Anders Albrechtsen
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Affiliation Centre of Bioinformatics, Faculty of Science, University of Copenhagen, Copenhagen, Denmark
- Augustine Kong
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Gisli Masson
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Affiliation deCODE Genetics, Reykjavik, Iceland
- Geng Tian
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Affiliation BGI-Shenzhen, Shenzhen, China
- Hongzhi Cao
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Affiliation BGI-Shenzhen, Shenzhen, China
- Chao Nie
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Affiliation BGI-Shenzhen, Shenzhen, China
- Karsten Kristiansen
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Affiliation Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark
- Lise Lotte Husemoen
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Affiliation Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
- Betina Thuesen
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Affiliation Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
- Yingrui Li
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Affiliation BGI-Shenzhen, Shenzhen, China
- Rasmus Nielsen
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Affiliations Centre of Bioinformatics, Faculty of Science, University of Copenhagen, Copenhagen, Denmark, Department of Integrative Biology, University of California, Berkeley, Berkeley, California, United States of America, Department of Statistics, University of California, Berkeley, Berkeley, California, United States of America
- Allan Linneberg
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Affiliation Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark
- Isleifur Olafsson
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Affiliation Landspitali, The National University Hospital of Iceland, Department of Clinical Biochemistry, Reykjavik, Iceland
- Gudmundur I. Eyjolfsson
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Affiliation Icelandic Medical Center (Laeknasetrid) Laboratory in Mjodd (RAM), Reykjavik, Iceland
- Torben Jørgensen
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Affiliations Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Medicine, University of Aalborg, Aalborg, Denmark
- Jun Wang
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Affiliations The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, BGI-Shenzhen, Shenzhen, China, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark
- Torben Hansen
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Affiliations The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
- Unnur Thorsteinsdottir
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Affiliations deCODE Genetics, Reykjavik, Iceland, University of Iceland Faculty of Medicine, Reykjavik, Iceland
- Kari Stefánsson
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* E-mail: kstefans@decode.is (K. Stefánsson); oluf@sund.ku.dk (O. Pedersen)
Affiliations deCODE Genetics, Reykjavik, Iceland, University of Iceland Faculty of Medicine, Reykjavik, Iceland
- Oluf Pedersen
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* E-mail: kstefans@decode.is (K. Stefánsson); oluf@sund.ku.dk (O. Pedersen)
Affiliations The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark, Hagedorn Research Institute, Gentofte, Denmark, Institute of Biomedical Science, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Competing Interests
I have read the journal's policy and declare that the authors from deCODE Genetics (P. Sulem, G. Thorleifsson, V. Steinthorsdottir, H. Bjarnason, D. F. Gudbjartsson, O. T. Magnusson, A. Kong, G. Masson, U. Thorsteinsdottir, and K. Stefánsson) are employees of deCODE Genetics or own stock options in deCODE Genetics. The remaining authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: N. Grarup, P. Sulem, C.H. Sandholt, T. Jørgensen, U. Thorsteinsdottir, K. Stefánsson, O. Pedersen. Performed the experiments: I. Olafsson, G.I. Eyjolfsson, A. Linneberg, L.L. Husemoen, B. Thuesen, T. Hansen, O. Pedersen, T. Jørgensen, P. Sulem, D.F. Gudbjartsson, H. Bjarnason, G. Thorleifsson, A. Kong, V. Steinthorsdottir, G. Masson, O.T. Magnusson, U. Thorsteinsdottir, K. Stefánsson, N. Grarup, C.H. Sandholt, T. Sparsø, A. Albrechtsen, G. Tian, H. Cao, C. Nie, K. Kristiansen, Y. Li, R. Nielsen, J. Wang. Analyzed the data: N. Grarup, P. Sulem, T.S. Ahluwalia, H. Bjarnason, T. Sparsø, A. Albrechtsen, A. Kong, G. Masson. Contributed reagents/materials/analysis tools: A. Albrechtsen, A. Kong, G. Masson. Wrote the paper: N. Grarup, P. Sulem, C.H. Sandholt, T. Jørgensen, U. Thorsteinsdottir, K. Stefánsson, O. Pedersen. Recruited participants study and collected clinical or paraclinical information: I. Olafsson, G.I. Eyjolfsson, A. Linneberg, L.L. Husemoen, B. Thuesen, N. Grarup, T. Hansen, O. Pedersen, T. Jørgensen. Developed, analyzed and interpreted Icelandic whole genome sequencing and chip-genotyping data: P. Sulem, H. Bjarnason, D.F. Gudbjartsson, G. Thorleifsson, A. Kong, V. Steinthorsdottir, G. Masson, O.T. Magnusson, U. Thorsteinsdottir, K. Stefánsson. Developed, analyzed, and interpreted Danish exome sequencing and chip-genotyping data: N. Grarup, C.H. Sandholt, T. Sparsø, A. Albrechtsen, G. Tian, H. Cao, C. Nie, K. Kristiansen, Y. Li, R. Nielsen, A. Linneberg, T. Jørgensen, J. Wang, T. Hansen, O. Pedersen.