About the Authors

Joshua C. Randall

Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Thomas W. Winkler

Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

Affiliation Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany

Zoltán Kutalik

Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

Sonja I. Berndt

Contributed equally to this work with: Joshua C. Randall, Thomas W. Winkler, Zoltán Kutalik, Sonja I. Berndt

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

Anne U. Jackson

Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Keri L. Monda

Affiliation Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Tuomas O. Kilpeläinen

Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Tõnu Esko

Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Reedik Mägi

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Estonian Genome Center, University of Tartu, Tartu, Estonia

Shengxu Li

Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America

Tsegaselassie Workalemahu

Affiliation Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

Mary F. Feitosa

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Damien C. Croteau-Chonka

Affiliation Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Felix R. Day

Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Tove Fall

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Teresa Ferreira

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Stefan Gustafsson

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Adam E. Locke

Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Iain Mathieson

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Andre Scherag

Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

Sailaja Vedantam

Affiliations Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America, Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Andrew R. Wood

Affiliation Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom

Liming Liang

Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Valgerdur Steinthorsdottir

Affiliation deCODE Genetics, Reykjavik, Iceland

Gudmar Thorleifsson

Affiliation deCODE Genetics, Reykjavik, Iceland

Emmanouil T. Dermitzakis

Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

Antigone S. Dimas

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Biomedical Sciences Research Center Al. Fleming, Vari, Greece

Fredrik Karpe

Affiliation Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Josine L. Min

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

George Nicholson

Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom, MRC Harwell, Harwell, United Kingdom

Deborah J. Clegg

Affiliation University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Thomas Person

Affiliation University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Jon P. Krohn

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Sabrina Bauer

Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

Christa Buechler

Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

Kristina Eisinger

Affiliation Regensburg University Medical Center, Innere Medizin I, Regensburg, Germany

DIAGRAM Consortium
Amélie Bonnefond

Affiliation CNRS UMR8199-IBL-Institut Pasteur de Lille, Lille, France

Philippe Froguel

Affiliations CNRS UMR8199-IBL-Institut Pasteur de Lille, Lille, France, Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom

MAGIC Investigators
Jouke-Jan Hottenga

Affiliation Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands

Inga Prokopenko

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

Lindsay L. Waite

Affiliation Hudson Alpha Institute for Biotechnology, Huntsville, Alabama, United States of America

Tamara B. Harris

Affiliation Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

Albert Vernon Smith

Affiliations Icelandic Heart Association, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland

Alan R. Shuldiner

Affiliations Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

Wendy L. McArdle

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Mark J. Caulfield

Affiliation Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Patricia B. Munroe

Affiliation Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Henrik Grönberg

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Yii-Der Ida Chen

Affiliations Department of OB/GYN and Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, California, United States of America

Guo Li

Affiliation Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America

Jacques S. Beckmann

Affiliations Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois (CHUV) University Hospital, Lausanne, Switzerland, Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

Toby Johnson

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland, Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Unnur Thorsteinsdottir

Affiliations deCODE Genetics, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland

Maris Teder-Laving

Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

Kay-Tee Khaw

Affiliation Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

Nicholas J. Wareham

Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Jing Hua Zhao

Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Najaf Amin

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands

Ben A. Oostra

Affiliations Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands, Centre for Medical Systems Biology & Netherlands Consortium on Healthy Aging, Leiden, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands

Aldi T. Kraja

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Michael A. Province

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

L. Adrienne Cupples

Affiliation Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

Nancy L. Heard-Costa

Affiliation Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America

Jaakko Kaprio

Affiliations National Institute for Health and Welfare, Unit for Child and Adolescent Psychiatry, Helsinki, Finland, Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Samuli Ripatti

Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

Ida Surakka

Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

Francis S. Collins

Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

Jouko Saramies

Affiliation South Karelia Central Hospital, Lappeenranta, Finland

Jaakko Tuomilehto

Affiliations Red RECAVA Grupo RD06/0014/0015, Hospital Universitario, La Paz, Madrid, Spain, Centre for Vascular Prevention, Danube-University Krems, Krems, Austria, National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland, South Ostrobothnia Central Hospital, Seinajoki, Finland

Antti Jula

Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Population Studies Unit, Turku, Finland

Veikko Salomaa

Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

Jeanette Erdmann

Affiliations Nordic Center of Cardiovascular Research (NCCR), Lübeck, Germany, Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany

Christian Hengstenberg

Affiliation Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany

Christina Loley

Affiliations Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany, Deutsches Herzzentrum München and DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

Heribert Schunkert

Affiliation Deutsches Herzzentrum München and DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

Claudia Lamina

Affiliation Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria

H. Erich Wichmann

Affiliations Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, and Klinikum Grosshadern, Munich, Germany

Eva Albrecht

Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Christian Gieger

Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Andrew A. Hicks

Affiliation Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano/Bozen, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany

Åsa Johansson

Affiliations Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, Uppsala Clinical Research Center, Uppsala University Hospital, Uppsala, Sweden

Peter P. Pramstaller

Affiliations Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano/Bozen, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany, Department of Neurology, General Central Hospital, Bolzano, Italy, Department of Neurology, University of Lübeck, Lübeck, Germany

Sekar Kathiresan

Affiliations Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Elizabeth K. Speliotes

Affiliations Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, United States of America

Brenda Penninx

Affiliation Department of Psychiatry, University Medical Centre Groningen, Groningen, The Netherlands

Anna-Liisa Hartikainen

Affiliation Department of Clinical Sciences/Obstetrics and Gynecology, University of Oulu, Oulu, Finland

Marjo-Riitta Jarvelin

Affiliations Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom, Institute of Health Sciences, University of Oulu, Oulu, Finland, Biocenter Oulu, University of Oulu, Oulu, Finland, National Institute for Health and Welfare, Oulu, Finland

Ulf Gyllensten

Affiliation Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

Dorret I. Boomsma

Affiliation Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands

Harry Campbell

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

James F. Wilson

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Stephen J. Chanock

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

Martin Farrall

Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Anuj Goel

Affiliation Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Carolina Medina-Gomez

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Fernando Rivadeneira

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Karol Estrada

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

André G. Uitterlinden

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Albert Hofman

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands

M. Carola Zillikens

Affiliations Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

Martin den Heijer

Affiliation Department of Internal Medicine, VU University Medical Centre, Amsterdam, The Netherlands

Lambertus A. Kiemeney

Affiliations Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Comprehensive Cancer Center East, Nijmegen, The Netherlands

Andrea Maschio

Affiliation Istituto di Neurogenetica e Neurofarmacologia del CNR, Monserrato, Cagliari, Italy

Per Hall

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Jonathan Tyrer

Affiliation Department of Oncology, University of Cambridge, Cambridge, United Kingdom

Alexander Teumer

Affiliation Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Henry Völzke

Affiliation Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Peter Kovacs

Affiliation Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany

Anke Tönjes

Affiliations University of Leipzig, IFB Adiposity Diseases, Leipzig, Germany, Department of Medicine, University of Leipzig, Leipzig, Germany

Massimo Mangino

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Tim D. Spector

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Caroline Hayward

Affiliation MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom

Igor Rudan

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Alistair S. Hall

Affiliation Division of Cardiovascular and Neuronal Remodelling, Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom

Nilesh J. Samani

Affiliations Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom, Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom

Antony Paul Attwood

Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, Department of Haematology, University of Cambridge, Cambridge, United Kingdom

Jennifer G. Sambrook

Affiliations Department of Haematology, University of Cambridge, Cambridge, United Kingdom, NHS Blood and Transplant, Cambridge Centre, Cambridge, United Kingdom

Joseph Hung

Affiliations School of Medicine and Pharmacology, The University of Western Australia, Nedlands, Western Austrailia, Australia, Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia

Lyle J. Palmer

Affiliations Genetic Epidemiology and Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Canada, Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Toronto, Canada

Marja-Liisa Lokki

Affiliation Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland

Juha Sinisalo

Affiliation Division of Cardiology, Cardiovascular Laboratory, Helsinki University Central Hospital, Helsinki, Finland

Gabrielle Boucher

Affiliation Montreal Heart Institute, Montreal, Quebec, Canada

Heikki Huikuri

Affiliation Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Oulu, Finland

Mattias Lorentzon

Affiliation Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Claes Ohlsson

Affiliation Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Niina Eklund

Affiliations Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

Johan G. Eriksson

Affiliations Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Helsinki University Central Hospital, Unit of General Practice, Helsinki, Finland

Cristina Barlassina

Affiliation University of Milan, Department of Medicine, Surgery and Dentistry, Milano, Italy

Carlo Rivolta

Affiliation Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

Ilja M. Nolte

Affiliation Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Harold Snieder

Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Melanie M. Van der Klauw

Affiliations LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Jana V. Van Vliet-Ostaptchouk

Affiliations LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Pablo V. Gejman

Affiliations University of Chicago, Chicago, Illinois, United States of America, Northshore University Healthsystem, Evanston, Ilinois, United States of America

Jianxin Shi

Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America

Kevin B. Jacobs

Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America, Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

Zhaoming Wang

Affiliations Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America, Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

Stephan J. L. Bakker

Affiliation Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Irene Mateo Leach

Affiliation Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Gerjan Navis

Affiliation Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Pim van der Harst

Affiliations Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Nicholas G. Martin

Affiliation Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

Sarah E. Medland

Affiliation Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

Grant W. Montgomery

Affiliation Molecular Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia

Jian Yang

Affiliation Queensland Statistical Genetics Laboratory, Queensland Institute of Medical Research, Queensland, Australia

Daniel I. Chasman

Affiliations Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Paul M. Ridker

Affiliations Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Lynda M. Rose

Affiliation Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Terho Lehtimäki

Affiliation Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere, Finland

Olli Raitakari

Affiliations Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland, The Department of Clinical Physiology, Turku University Hospital, Turku, Finland

Devin Absher

Affiliation Hudson Alpha Institute for Biotechnology, Huntsville, Alabama, United States of America

Carlos Iribarren

Affiliation Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America

Hanneke Basart

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

Kees G. Hovingh

Affiliation Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

Elina Hyppönen

Affiliation Centre For Paediatric Epidemiolgy and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom

Chris Power

Affiliation Centre For Paediatric Epidemiolgy and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom

Denise Anderson

Affiliations Telethon Institute for Child Health Research, West Perth, Western Australia, Australia, Centre for Child Health Research, The University of Western Australia, Perth, Australia

John P. Beilby

Affiliations Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia, PathWest Laboratory of Western Australia, Department of Molecular Genetics, QEII Medical Centre, Nedlands, Western Australia, Australia, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia

Jennie Hui

Affiliations Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia, PathWest Laboratory of Western Australia, Department of Molecular Genetics, QEII Medical Centre, Nedlands, Western Australia, Australia, School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia, School of Population Health, The University of Western Australia, Nedlands, Western Austrailia, Australia

Jennifer Jolley

Affiliation Department of Haematology, University of Cambridge, Cambridge, United Kingdom

Hendrik Sager

Affiliation Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany

Stefan R. Bornstein

Affiliation Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany

Peter E. H. Schwarz

Affiliation Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany

Kati Kristiansson

Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

Markus Perola

Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Department of Chronic Disease Prevention, Unit of Public Health Genomics, Helsinki, Finland

Jaana Lindström

Affiliation National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland

Amy J. Swift

Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

Matti Uusitupa

Affiliations Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland, Research Unit, Kuopio University Hospital, Kuopio, Finland

Mustafa Atalay

Affiliation Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland

Timo A. Lakka

Affiliations Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland

Rainer Rauramaa

Affiliations Kuopio Research Institute of Exercise Medicine, Kuopio, Finland, Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland

Jennifer L. Bolton

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Gerry Fowkes

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Ross M. Fraser

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Jackie F. Price

Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

Krista Fischer

Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

Kaarel Krjutškov

Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

Andres Metspalu

Affiliation Estonian Genome Center, University of Tartu, Tartu, Estonia

Evelin Mihailov

Affiliations Estonian Genome Center, University of Tartu, Tartu, Estonia, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

Claudia Langenberg

Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Department of Epidemiology and Public Health, University College London, London, United Kingdom

Jian'an Luan

Affiliation MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom

Ken K. Ong

Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, MRC Unit for Lifelong Health & Ageing, London, United Kingdom

Peter S. Chines

Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

Sirkka M. Keinanen-Kiukaanniemi

Affiliations Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland, Unit of General Practice, Oulu University Hospital, Oulu, Finland

Timo E. Saaristo

Affiliations Finnish Diabetes Association, Tampere, Finland, Pirkanmaa Hospital District, Tampere, Finland

Sarah Edkins

Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Paul W. Franks

Affiliations Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden

Göran Hallmans

Affiliation Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden

Dmitry Shungin

Affiliations Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Lund University, Malmö, Sweden, Department of Public Health & Clinical Medicine, Umeå University,Umeå, Sweden, Department of Odontology, Umeå University, Umea, Sweden

Andrew David Morris

Affiliation Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom

Colin N. A. Palmer

Affiliation Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom

Raimund Erbel

Affiliation Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen, Germany

Susanne Moebus

Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

Markus M. Nöthen

Affiliations Institute of Human Genetics, University of Bonn, Bonn, Germany, Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany

Sonali Pechlivanis

Affiliation Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

Kristian Hveem

Affiliation HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway

Narisu Narisu

Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

Anders Hamsten

Affiliation Atherosclerosis Research Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Steve E. Humphries

Affiliation Cardiovascular Genetics, British Heart Foundation Laboratories, Rayne Building, University College London, London, United Kingdom

Rona J. Strawbridge

Affiliation Atherosclerosis Research Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

Elena Tremoli

Affiliation Department of Pharmacological Sciences, University of Milan, Monzino Cardiology Center, IRCCS, Milan, Italy

Harald Grallert

Affiliation Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Barbara Thorand

Affiliation Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Thomas Illig

Affiliations Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

Wolfgang Koenig

Affiliation Department of Internal Medicine II – Cardiology, University of Ulm Medical Center, Ulm, Germany

Martina Müller-Nurasyid

Affiliations Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Annette Peters

Affiliation Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Bernhard O. Boehm

Affiliation Division of Endocrinology and Diabetes, Department of Medicine, University Hospital, Ulm, Germany

Marcus E. Kleber

Affiliations LURIC Study nonprofit LLC, Freiburg, Germany, Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany

Winfried März

Affiliations Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany, Synlab Academy, Mannheim, Germany

Bernhard R. Winkelmann

Affiliation Cardiology Group, Frankfurt-Sachsenhausen, Germany

Johanna Kuusisto

Affiliation Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

Markku Laakso

Affiliation Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

Dominique Arveiler

Affiliation Department of Epidemiology and Public Health, Faculty of Medicine, Strasbourg, France

Giancarlo Cesana

Affiliation Department of Clinical Medicine, University of Milano-Bicocca, Monza, Italy

Kari Kuulasmaa

Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

Jarmo Virtamo

Affiliation National Institute for Health and Welfare, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland

John W. G. Yarnell

Affiliation Centre for Public Health, Queen's University, Belfast, United Kingdom

Diana Kuh

Affiliation MRC Unit for Lifelong Health & Ageing, London, United Kingdom

Andrew Wong

Affiliation MRC Unit for Lifelong Health & Ageing, London, United Kingdom

Lars Lind

Affiliation Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala, Sweden

Ulf de Faire

Affiliation Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Bruna Gigante

Affiliation Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Patrik K. E. Magnusson

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Nancy L. Pedersen

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

George Dedoussis

Affiliation Department of Dietetics-Nutrition, Harokopio University, Athens, Greece

Maria Dimitriou

Affiliation Department of Dietetics-Nutrition, Harokopio University, Athens, Greece

Genovefa Kolovou

Affiliation 1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece

Stavroula Kanoni

Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Kathleen Stirrups

Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Lori L. Bonnycastle

Affiliation Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, United States of America

Inger Njølstad

Affiliation Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

Tom Wilsgaard

Affiliation Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

Andrea Ganna

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Emil Rehnberg

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Aroon Hingorani

Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

Mika Kivimaki

Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

Meena Kumari

Affiliation Department of Epidemiology and Public Health, University College London, London, United Kingdom

Themistocles L. Assimes

Affiliation Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America

Inês Barroso

Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom, University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, United Kingdom

Michael Boehnke

Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Ingrid B. Borecki

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Panos Deloukas

Affiliation Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Caroline S. Fox

Affiliation Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, United States of America

Timothy Frayling

Affiliation Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom

Leif C. Groop

Affiliation Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden

Talin Haritunians

Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

David Hunter

Affiliations Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Erik Ingelsson

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Robert Kaplan

Affiliation Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, United States of America

Karen L. Mohlke

Affiliation Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America

Jeffrey R. O'Connell

Affiliation Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

David Schlessinger

Affiliation Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, United States of America

David P. Strachan

Affiliation Division of Community Health Sciences, St George's, University of London, London, United Kingdom

Kari Stefansson

Affiliations deCODE Genetics, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavík, Iceland

Cornelia M. van Duijn

Affiliations Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands, Center of Medical Systems Biology, Leiden University Medical Center, Leiden, The Netherlands

Gonçalo R. Abecasis

Affiliation Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

Mark I. McCarthy

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom, Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom

Joel N. Hirschhorn

Affiliations Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, United States of America, Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Lu Qi

Affiliations Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Ruth J. F. Loos

ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

These authors supervised this work jointly.

Affiliations MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom, Genetics of Obesity and Related Metabolic Traits Program,The Charles Bronfman Institute of Personalized Medicine, Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York, United States of America

Cecilia M. Lindgren

ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

These authors supervised this work jointly.

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Kari E. North

ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

These authors supervised this work jointly.

Affiliation Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Iris M. Heid

ruth.loos@mssm.edu (RJFL); celi@well.ox.ac.uk (CML); kari_north@unc.edu (KEN); iris.heid@klinik.uni-regensburg.de (IMH)

These authors supervised this work jointly.

Affiliations Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

Competing Interests

I have read the journal's policy and we have the following conflicts: Kari Stefansson, Valgerdur Steinthorsdottir, and Gudmar Thorleifsson are employed by deCODE Genetics with stock/stock options in the company. Inês Barroso and spouse own stock in Incyte Ltd and GlaxoSmithKline. Nilesh J Samani holds a Chair supported by the British Heart Foundation and is an NIHR Senior Investigator.

Author Contributions

Gender Working group: G. R. Abecasis, S. I. Berndt, T. Esko, M. F. Feitosa, I. M. Heid, J. N. Hirschhorn, A. U. Jackson, T. O. Kilpeläinen, Z. Kutalik, S. Li, C. M. Lindgren, R. J. F. Loos, M. I. McCarthy, R. Mägi, K. L. Monda, K. E. North, L. Qi, J. C. Randall, T. W. Winkler, T. Workalemahu. Data preparation & cleaning: D. C. Croteau-Chonka, F. R. Day, T. Esko, T. Fall, T. Ferreira, S. Gustafsson, A. E. Locke, I. Mathieson, A. Scherag, S. Vedantam, T. W. Winkler, A. R. Wood. eQTL in human tissue and mouse models: S. Bauer, C. Buechler, D. J. Clegg, E. T. Dermitzakis, A. S. Dimas, K. Eisinger, F. Karpe, J. P. Krohn, L. Liang, M. I. McCarthy, J. L. Min, G. Nicholson, T. Person, V. Steinthorsdottir, G. Thorleifsson. Study-specific analyses: G. R. Abecasis, E. Albrecht, N. Amin, D. Anderson, A. P. Attwood, C. Barlassina, S. I. Berndt, A. Bonnefond, G. Boucher, D. I. Chasman, L. A. Cupples, M. den Heijer, A. S. Dimas, N. Eklund, T. Esko, K. Estrada, T. Fall, M. Farrall, M. F. Feitosa, K. Fischer, P. W. Franks, R. M. Fraser, A. Ganna, A. Goel, S. Gustafsson, P. van der Harst, N. L. Heard-Costa, I. M. Heid, J-J. Hottenga, E. Hyppönen, E. Ingelsson, Å. Johansson, T. Johnson, S. Kanoni, M. E. Kleber, K. Kristiansson, C. Lamina, T. Lehtimäki, G. Li, C. M. Lindgren, C. Loley, M. Lorentzon, J. Luan, P. K. E. Magnusson, M. Mangino, I. Mateo Leach, C. Medina-Gomez, S. E. Medland, R. Mägi, E. Mihailov, J. L. Min, M. Müller-Nurasyid, K. L. Monda, G. Nicholson, I. M. Nolte, K. E. North, J. R. O'Connell, C. Ohlsson, K. K. Ong, S. Pechlivanis, T. Person, I. Prokopenko, L. Qi, O. Raitakari, J. C. Randall, E. Rehnberg, S. Ripatti, F. Rivadeneira, J. G. Sambrook, J. Shi, D. Shungin, A. V. Smith, E. K. Speliotes, V. Salomaa, D. P. Strachan, R. J. Strawbridge, I. Surakka, A. Teumer, G. Thorleifsson, J. Tyrer, S. Vedantam, J. V. Van Vliet-Ostaptchouk, L. L. Waite, Z. Wang, T. W. Winkler, A. Wong, J. Yang, J. H. Zhao, L.M. Rose. Study-specific phenotyping: S. J. L. Bakker, H. Basart, S. I. Berndt, I. B. Borecki, M. den Heijer, M. Dimitriou, C. M. van Duijn, M. F. Feitosa, K. Fischer, G. Fowkes, C. S. Fox, P. W. Franks, P. V. Gejman, H. Grönberg., U. Gyllensten, A. S. Hall, P. Hall, G. Hallmans, A-L. Hartikainen, H. Huikuri, J. Hung, E. Hyppönen, E. Ingelsson, Å. Johansson, J. Jolley, A. Jula, J. Kaprio, F. Karpe, K-T. Khaw, M. M. Van der Klauw, G. Kolovou, P. Kovacs, D. Kuh, M. Kumari, L. Lind, J. Lindström, M-L. Lokki, R. J. F. Loos, M. Lorentzon, P. K. E. Magnusson, M. Mangino, N. G. Martin, M. I. McCarthy, A. Metspalu, A. D. Morris, G. Navis, C. Ohlsson, B. A. Oostra, L. J. Palmer, C. N. A. Palmer, N. L. Pedersen, A. Peters, C. Power, M. A. Province, L. Qi, O. Raitakari, F. Rivadeneira, H. Sager, V. Salomaa, N. J. Samani, A. R. Shuldiner, D. Shungin, J. Sinisalo, T. D. Spector, D. P. Strachan, M. Teder-Laving, B. Thorand, A. Tönjes, E. Tremoli, A. G. Uitterlinden, H. Völzke, N. J. Wareham, T. Wilsgaard, M. C. Zillikens. Study-specific genotyping: D. Absher, M. Atalay, I. Barroso, J. P. Beilby, J. L. Bolton, L. L. Bonnycastle, I. B. Borecki, S. J. Chanock, D. I. Chasman, Y-D. I. Chen, P. S. Chines, C. M. van Duijn, S. Edkins, T. Esko, K. Estrada, P. V. Gejman, B. Gigante, H. Grallert, H. Grönberg, A. S. Hall, P. Hall, C. Hayward, A. A. Hicks, J-J. Hottenga, T. Haritunians, J. Hui, D. Hunter, T. Illig, E. Ingelsson, K. B. Jacobs, Å. Johansson, A. T. Kraja, K. KrjutÅ¡kov, D. Kuh, C. Lamina, T. Lehtimäki, L. Lind, M. Lorentzon, J. Luan, P. K. E. Magnusson, M. Mangino, N. G. Martin, A. Maschio, W. L. McArdle, M. I. McCarthy, C. Medina-Gomez, G. W. Montgomery, N. Narisu, M. M. Nöthen, C. Ohlsson, K. K. Ong, B. A. Oostra, L. J. Palmer, C. N. A. Palmer, N. L. Pedersen, M. A. Province, S. Ripatti, F. Rivadeneira, N. J. Samani, K. Stirrups, I. Surakka, A. J. Swift, M. Teder-Laving, A. G. Uitterlinden, Z. Wang, J. F. Wilson, A. Wong. Writing Group: I. M. Heid, K. E. North, Z. Kutalik, C. M. Lindgren, R. J. F. Loos, S. I. Berndt, J. C. Randall, T. W. Winkler. Study-specific management: G. R. Abecasis, D. Arveiler, T. L. Assimes, C. Barlassina, J. S. Beckmann, J. P. Beilby, S. I. Berndt, B. O. Boehm, D. I. Boomsma, I. B. Borecki, S. R. Bornstein, G. Cesana, H. Campbell, M. J. Caulfield, S. J. Chanock, D. J. Clegg, F. S. Collins, L. A. Cupples, G. Dedoussis, U. de Faire, P. Deloukas, E. T. Dermitzakis, C. M. van Duijn, R. Erbel, J. Erdmann, J. G. Eriksson, M. Farrall, C. S. Fox, P. W. Franks, P. Froguel, P. V. Gejman, C. Gieger, L. C. Groop, U. Gyllensten, A. S. Hall, A. Hamsten, T. B. Harris, P. van der Harst, I. M. Heid, C. Hengstenberg, A. A. Hicks, A. Hingorani, J. N. Hirschhorn, A. Hofman, K. G. Hovingh, J. Hui, H. Huikuri, S. E. Humphries, K. Hveem, T. Illig, E. Ingelsson, C. Iribarren, M-R. Jarvelin, A. Jula, J. Kaprio, S. Kathiresan, S. M. Keinanen-Kiukaanniemi, K-T. Khaw, L. A. Kiemeney, M. Kivimaki, M. M. Van der Klauw, W. Koenig, D. Kuh, K. Kuulasmaa, J. Kuusisto, M. Laakso, T. A. Lakka, C. Langenberg, T. Lehtimäki, C. M. Lindgren, R. J. F. Loos, N. G. Martin, M. I. McCarthy, A. Metspalu, S. Moebus, G. W. Montgomery, A. D. Morris, W. März, P. B. Munroe, I. Njølstad, K. E. North, J. R. O'Connell, C. Ohlsson, B. A. Oostra, L. J. Palmer, C. N. A. Palmer, B. Penninx, M. Perola, A. Peters, C. Power, P. P. Pramstaller, J. F. Price, M. A. Province, L. Qi, O. Raitakari, R. Rauramaa, P. M. Ridker, S. Ripatti, F. Rivadeneira, C. Rivolta, I. Rudan, A. R. Shuldiner, T. E. Saaristo, V. Salomaa, N. J. Samani, J. Saramies, H. Schunkert, P. E. H. Schwarz, J. Sinisalo, H. Snieder, T. D. Spector, K. Stefansson, D. P. Strachan, I. Surakka, A. Tönjes, J. Tuomilehto, A. G. Uitterlinden, M. Uusitupa, J. Virtamo, N. J. Wareham, H. E. Wichmann, J. F. Wilson, B. R. Winkelmann, J. W. G. Yarnell. Steering Committee: G. R. Abecasis, T. L. Assimes, I. Barroso, S. I. Berndt, M. Boehnke, I. B. Borecki, P. Deloukas, C. M. van Duijn, C. S. Fox, T. Frayling, L. C. Groop, T. Haritunians, I. M. Heid, D. Hunter, E. Ingelsson, R. Kaplan, R. J. F. Loos, M. I. McCarthy, K. L. Mohlke, K. E. North, J. R. O'Connell, D. Schlessinger, D. P. Strachan, U. Thorsteinsdottir.