About the Authors

Alexandra M. Lopes

Contributed equally to this work with: Alexandra M. Lopes, Kenneth I. Aston

alopes@ipatimup.pt (AML); dconrad@genetics.wustl.edu (DFC)

Affiliation Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal

Kenneth I. Aston

Contributed equally to this work with: Alexandra M. Lopes, Kenneth I. Aston

Affiliation Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

Emma Thompson

Affiliation Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

Filipa Carvalho

Affiliation Department of Genetics, Faculty of Medicine, University of Porto, Porto, Portugal

João Gonçalves

Affiliation Department of Human Genetics, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal

Ni Huang

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Rune Matthiesen

Affiliation Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal

Michiel J. Noordam

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Inés Quintela

Affiliation Genomics Medicine Group, National Genotyping Center, University of Santiago de Compostela, Santiago de Compostela, Spain

Avinash Ramu

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Catarina Seabra

Affiliation Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal

Amy B. Wilfert

Affiliation Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Juncheng Dai

Affiliation Department of Epidemiology and Biostatistics and Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China

Jonathan M. Downie

Affiliation Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

Susana Fernandes

Affiliation Department of Genetics, Faculty of Medicine, University of Porto, Porto, Portugal

Xuejiang Guo

Affiliations State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China

Jiahao Sha

Affiliations State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China

António Amorim

Affiliations Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal, Faculty of Sciences, University of Porto, Porto, Portugal

Alberto Barros

Affiliations Department of Genetics, Faculty of Medicine, University of Porto, Porto, Portugal, Centre for Reproductive Genetics Alberto Barros, Porto, Portugal

Angel Carracedo

Affiliations Genomics Medicine Group, National Genotyping Center, University of Santiago de Compostela, Santiago de Compostela, Spain, Galician Foundation of Genomic Medicine and University of Santiago de Compostela, CIBERER, Santiago de Compostela, Spain

Zhibin Hu

Affiliations Department of Epidemiology and Biostatistics and Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China

Matthew E. Hurles

Affiliation Genome Mutation and Genetic Disease Group, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Sergey Moskovtsev

Affiliations CReATe Fertility Center, University of Toronto, Toronto, Canada, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Canada

Carole Ober

Affiliations Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America, Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois, United States of America

Darius A. Paduch

Affiliation Department of Urology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York, United States of America

Joshua D. Schiffman

Affiliations Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Center for Children's Cancer Research (C3R), Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Division of Pediatric Hematology/Oncology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

Peter N. Schlegel

Affiliation Department of Urology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York, United States of America

Mário Sousa

Affiliation Laboratory of Cell Biology, UMIB, ICBAS, University of Porto, Porto, Portugal

Douglas T. Carrell

Affiliations Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

Donald F. Conrad

alopes@ipatimup.pt (AML); dconrad@genetics.wustl.edu (DFC)

Affiliations Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AML DTC KIA DFC. Performed the experiments: KIA AML DFC FC JG SF MS AB MJN ET CS AC. Analyzed the data: DFC AML KIA RM NH ET JMD JD AR ABW. Contributed reagents/materials/analysis tools: AML CO XG DAP PNS JS ZH SM IQ JDS DFC DTC. Wrote the paper: DFC. Participated in the interpretation of results: AA MEH. Assisted with writing the manuscript: KIA DTC AML CO JDS PNS.