About the Authors

John P. Miller

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Bridget E. Yates

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Ismael Al-Ramahi

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Ari E. Berman

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Mario Sanhueza

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Eugene Kim

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Maria de Haro

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Francesco DeGiacomo

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Cameron Torcassi

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Jennifer Holcomb

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Juliette Gafni

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Sean D. Mooney

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Juan Botas

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Lisa M. Ellerby

lellerby@buckinstitute.org (LME); rhughes@buckinstitute.org (REH)

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Robert E. Hughes

lellerby@buckinstitute.org (LME); rhughes@buckinstitute.org (REH)

Affiliation The Buck Institute for Research on Aging, Novato, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JPM BEY IA-R AEB SDM JB LME REH. Performed the experiments: JPM BEY IA-R AEB MS EK MdH FD CT JH JG LME. Analyzed the data: JPM BEY IA-R AEB FD JG SDM JB LME REH. Contributed reagents/materials/analysis tools: SDM JB LME REH. Wrote the paper: JPM BEY IA-R AEB JB LME REH.