About the Authors

Rebecca E. McIntyre

Affiliation Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Pavithra Lakshminarasimhan Chavali

Affiliation Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre and Department of Oncology, University of Cambridge, Cambridge, United Kingdom

Ozama Ismail

Contributed equally to this work with: Ozama Ismail, Damian M. Carragher, Gabriela Sanchez-Andrade

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Damian M. Carragher

Contributed equally to this work with: Ozama Ismail, Damian M. Carragher, Gabriela Sanchez-Andrade

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Gabriela Sanchez-Andrade

Contributed equally to this work with: Ozama Ismail, Damian M. Carragher, Gabriela Sanchez-Andrade

Affiliation Genetics of Instinctive Behaviour, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Josep V. Forment

Affiliation The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Beiyuan Fu

Affiliation Molecular Cytogenetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Martin Del Castillo Velasco-Herrera

Affiliation Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Andrew Edwards

Affiliation Wellcome Trust Center for Human Genetics, Oxford, United Kingdom

Louise van der Weyden

Affiliation Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Fengtang Yang

Affiliation Molecular Cytogenetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Sanger Mouse Genetics Project

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Ramiro Ramirez-Solis

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Jeanne Estabel

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Ferdia A. Gallagher

Affiliation Department of Radiology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

Darren W. Logan

Affiliation Genetics of Instinctive Behaviour, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Mark J. Arends

Affiliation Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom

Stephen H. Tsang

Affiliations Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa, United States of America, Bernard and Shirlee Brown Glaucoma Laboratory, Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Vinit B. Mahajan

Affiliation Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa, United States of America

Cheryl L. Scudamore

Affiliation Department of Pathology and Infectious Diseases, Royal Veterinary College, London, United Kingdom

Jacqueline K. White

Affiliation Mouse Genetics Project, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Stephen P. Jackson

Affiliation The Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Fanni Gergely

Affiliation Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre and Department of Oncology, University of Cambridge, Cambridge, United Kingdom

David J. Adams

da1@sanger.ac.uk

Affiliation Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DJA JKW RR-S REM GS-A OI DMC AE SPJ. Performed the experiments: REM OI DMC GS-A MDCV-H AE VBM PLC JVF BF FY JE LvdW JKW MJA. Analyzed the data: REM OI GS-A MDCV-H AE FAG DWL MJA SHT SMGP CLS FG. Wrote the paper: REM FG SPJ DJA.