About the Authors

Nicole C. Riddle

Contributed equally to this work with: Nicole C. Riddle, Youngsook L. Jung, Tingting Gu

Affiliation Department of Biology, Washington University in St. Louis, St. Louis, Missouri, United States of America

Youngsook L. Jung

Contributed equally to this work with: Nicole C. Riddle, Youngsook L. Jung, Tingting Gu

Affiliation Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America

Tingting Gu

Contributed equally to this work with: Nicole C. Riddle, Youngsook L. Jung, Tingting Gu

Affiliation Department of Biology, Washington University in St. Louis, St. Louis, Missouri, United States of America

Artyom A. Alekseyenko

Affiliation Division of Genetics, Department of Medicine, Brigham and Women's Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Dalal Asker

Affiliations Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America, Food Science and Technology Department, Faculty of Agriculture, Alexandria University, Alexandria, Egypt

Hongxing Gui

Affiliation Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

Peter V. Kharchenko

Affiliation Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America

Aki Minoda

Affiliations Department of Molecular and Cell Biology, University of California Berkeley, California, United States of America, Department of Genome Dynamics, Lawrence Berkeley National Lab, Berkeley, California, United States of America

Annette Plachetka

Affiliation Division of Genetics, Department of Medicine, Brigham and Women's Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Yuri B. Schwartz

Affiliations Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America, Department of Molecular Biology, Umea University, Umea, Sweden

Michael Y. Tolstorukov

Affiliation Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America

Mitzi I. Kuroda

Affiliation Division of Genetics, Department of Medicine, Brigham and Women's Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Vincenzo Pirrotta

Affiliation Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey, United States of America

Gary H. Karpen

Affiliations Department of Molecular and Cell Biology, University of California Berkeley, California, United States of America, Department of Genome Dynamics, Lawrence Berkeley National Lab, Berkeley, California, United States of America

Peter J. Park

peter_park@hms.harvard.edu (PJP); riddlenc@biology2.wustl.edu (SCRE)

Affiliation Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America

Sarah C. R. Elgin

peter_park@hms.harvard.edu (PJP); riddlenc@biology2.wustl.edu (SCRE)

Affiliation Department of Biology, Washington University in St. Louis, St. Louis, Missouri, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NCR TG MIK VP GHK PJP SCRE. Performed the experiments: NCR TG AAA DA HG AM AP YBS. Analyzed the data: NCR TG YLJ. Contributed reagents/materials/analysis tools: PVK MYT. Wrote the paper: NCR YLJ TG PJP SCRE.