About the Authors

Wei-Chung Chiang

Contributed equally to this work with: Wei-Chung Chiang, Daniel X. Tishkoff, Bo Yang

Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

Daniel X. Tishkoff

Contributed equally to this work with: Wei-Chung Chiang, Daniel X. Tishkoff, Bo Yang

Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Bo Yang

Contributed equally to this work with: Wei-Chung Chiang, Daniel X. Tishkoff, Bo Yang

Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Joshua Wilson-Grady

Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Xiaokun Yu

Affiliation Department of Internal Medicine, Division of Geriatric Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

Travis Mazer

Affiliation Department of Internal Medicine, Division of Geriatric Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

Mark Eckersdorff

Address Current address: Regeneron Pharmaceuticals, Tarrytown, New York, United States of America

Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Steven P. Gygi

Affiliation Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

David B. Lombard

davidlom@umich.edu (DBL); aolinshu@umich.edu (A-LH)

Affiliations Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America, Institute of Gerontology and the Geriatrics Center, University of Michigan, Ann Arbor, Michigan, United States of America

Ao-Lin Hsu

davidlom@umich.edu (DBL); aolinshu@umich.edu (A-LH)

Affiliations Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, Division of Geriatric Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Institute of Gerontology and the Geriatrics Center, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: A-LH DBL. Performed the experiments: W-CC DXT BY JW-G XY TM ME A-LH. Analyzed the data: W-CC DXT BY JW-G XY SPG DBL A-LH . Wrote the paper: DBL A-LH.