About the Authors

Thomas M. Wishart

Affiliations Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom, Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Division of Neurobiology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom

Timothy M. Rooney

Affiliation Department of Neurobiology, Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Douglas J. Lamont

Affiliation FingerPrints Proteomics Facility, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Ann K. Wright

Affiliations Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom, Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom

A. Jennifer Morton

Affiliation Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom

Mandy Jackson

Affiliations Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom, Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom

Marc R. Freeman

Affiliation Department of Neurobiology, Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Thomas H. Gillingwater

T.Gillingwater@ed.ac.uk

Affiliations Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom, Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TMW MRF THG. Performed the experiments: TMW TMR DJL AKW THG. Analyzed the data: TMW TMR MRF THG. Contributed reagents/materials/analysis tools: AJM MJ. Wrote the paper: TMW TMR MRF THG.