About the Authors

Michael Inouye
Medical Systems Biology, Departments of Pathology and of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

Michael Inouye
Immunology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

Samuli Ripatti, Johannes Kettunen, Pirkka-Pekka Laurila, Aarno Palotie
Institute of Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland

Samuli Ripatti, Johannes Kettunen, Pirkka-Pekka Laurila, Markus Perola, Veikko Salomaa
Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland

Samuli Ripatti, Aarno Palotie
Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom

Leo-Pekka Lyytikäinen, Niku Oksala, Terho Lehtimäki
Department of Clinical Chemistry, Fimlab Laboratories, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland

Niku Oksala
Division of Vascular Surgery, Department of Surgery, Tampere University Hospital, Tampere, Finland

Pirkka-Pekka Laurila, Aarno Palotie
Department of Medical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Antti J. Kangas, Pasi Soininen, Markku J. Savolainen, Mika Ala-Korpela
Computational Medicine, Institute of Clinical Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland

Pasi Soininen, Mika Ala-Korpela
NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland

Markku J. Savolainen, Marjo-Riitta Järvelin
Biocenter Oulu, University of Oulu, Oulu, Finland

Markku J. Savolainen, Mika Ala-Korpela
Department of Internal Medicine, Clinical Research Center, University of Oulu, Oulu, Finland

Jorma Viikari
Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland

Mika Kähönen
Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland

Olli Raitakari
Research Centre of Applied and Preventive Cardiovascular Medicine and Department of Clinical Physiology, University of Turku and Turku University Hospital, Turku, Finland

Marja-Riitta Taskinen
Department of Medicine, University of Helsinki, Helsinki, Finland

Marjo-Riitta Järvelin, Mika Ala-Korpela
Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom

Marjo-Riitta Järvelin
Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland

Aarno Palotie, Paul I. W. de Bakker
Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

Paul I. W. de Bakker
Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Paul I. W. de Bakker
Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

Paul I. W. de Bakker
Department of Epidemiology, University Medical Center Utrecht, Utrecht, The Netherlands

Corresponding Author

minouye@unimelb.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MI PIWdB. Performed the experiments: NO AJK PS. Analyzed the data: MI SR JK L-PL P-PL PIWdB. Contributed reagents/materials/analysis tools: JK JV MK MP VS OR TL M-RJ MA-K AP MJS. Wrote the paper: MI SR M-RT AP PIWdB.